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 12194 (302) The Evidence-Based Protocol Development for Prevention of Bronchopulmonary Dysplasia in Very Low Birthweight Infants $15.00   
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12194 (302) The Evidence-Based Protocol Development for Prevention of Bronchopulmonary Dysplasia in Very Low Birthweight Infants
Sara L. Dubin, MSN ARNP NNP-BC

Abstract
Very low birth weight (VLBW) infants are at risk for multiple morbidities including BPD, bronchopulmonary dysplasia. The etiopathogenesis of BPD is known to be multi-factorial. Therefore any single clinical intervention will not lessen the occurrence of this complex disease in VLBW infants. This session will discuss an evidence-based, multi-pronged plan of care for VLBW infants to reduce the severity of BPD. Among topics to be discussed include the various definitions found in the literature defining BPD including the classification systems, review of the pathophysiology of BPD and a multi-pronged approach we developed in our unit for the prevention and reduction in severity of BPD. The multi-pronged approach includes such therapies as prenatal interventions, surfactant therapy, oxygen saturation targeting, evaluation and treatment of patent ductus arteriosus, early caffeine administration, nutritional supplementation, and prophylactic inhaled nitric oxide treatment. Each topic will include a brief pathophysiology review of the intervention and relationship to BPD and a review of current literature supporting the use of these clinical interventions.

Learning Objectives
1. Define bronchopulmonary dysplasia (BPD) using traditional and current definitions.
2. Describe a multipronged protocol for prevention of BPD.
3. Explain the prophylatic use of inhaled nitric oxide in the premature infant to prevent BPD.

Bibliography
Kinsella, J. & et.al. (2006)Early Inhaled Nitric Oxide Therapy in Premature Newborns with Respiratory Failure. The New England Journal of Medicine., 355(4), 354-364.

Barrington, K. & Finer, N. (2007). Inhaled Nitric Oxide for Preterm Infants: A Systematic Review. Pediatrics., 120(5), 1088-1099.

Deakins, K. (2009). Bronchopulmonary Dysplasia. Respiratory Care., 54(9), 1252-1262.

Arul, N. & Konduri, G. (2009). Inhaled Nitric Oxide for Preterm Neonates. Clinical Perinatology., 36, 43-61.

 






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